SIMON HAENDELER

Freelancing Bioinformatician and Data Scientist Contact for inquiries

Projects

PhantomBuster

Lineage Tracing Pipeline
syntonym/phantombuster

Menqu

High-Throughput qPCR analysis tool
syntonym/qpcr_analysis

Calsiprovis

Calcium Signal Propagation Speed Analysis
syntonym/signal_propagation

Pyrganoid

Brain Organoid Growth Modelling
cibiv/pyrganoid

Experience

Freelancing Bioinformatician

Toronto, Canada
2025-present
CRISPR-LICHT analysis for the Nicolis Lab 2025

Identification of proliferation effects of gene knockouts

ATAC-seq Analysis for the Latos Lab 2025

Identification of open chromatin regions in hSC using PEPATAC and TOBIAS.

PhD Student

Vienna, Austria
CIBIV, University of Vienna 2020-2024
Auer Signal GmbH 2015-2017

Academic Publications

PhantomBuster – A tool for removing phantoms in sequencing-based lineage tracing experiments

Haendeler S*, Pflug FG, Schroeder B, Lindenhofer D, Esk C. in preperation

Cerebral organoids display dynamic clonal growth and tunable tissue replenishment

Lindenhofer D*, Haendeler S*, Esk C*, Littleboy JB*, Avalos CB, Naas J, Pflug FG, van de Ven EGP, Reumann D, Baffet AD, von Haeseler A, Knoblich JA. Nature Cell Biology. 2024-05-07. DOI 10.1038/s41556-024-01412-z

Neutral competition explains the clonal composition of neural organoids

Pflug FG*, Haendeler S, Esk C, Lindenhofer D, Knoblich JA, von Haeseler A. PLoS Comput Biol. 2024-04-22. DOI 10.1371/journal.pcbi.1012054

Multi-chamber cardioids unravel human heart development and cardiac defects

Schmidt C*, Deyett A*, Ilmer T, Haendeler S, Caballero AT, Novatchkova M, Netzer MA, Ginistrelli LC, Juncosa EM, Bhattacharya T, Mujadzic A, Pimpale L, Jahnel SM, Cirigliano M, Reumann D, Tavernini K, Papai N, Hering S, Hofbauer P, Mendjan S. Cell. 2023-12-07. DOI 10.1016/j.cell.2023.10.030

A human tissue screen identifies a regulator of ER secretion as a brain-size determinant

Esk C*, Lindenhofer D*, Haendeler S, Wester RA, Pflug F, Schroeder B, Bagley JA, Elling U, Zuber J, von Haeseler A, Knoblich JA. Science. 2020-11-20. DOI 10.1126/science.abb5390
* indicates (Co)-first author(s).